Compile Data Set for Download or QSAR
maximum 50k data
Found 64 of ic50 data for polymerid = 50000995
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM615970(US20230271957, Example 2)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618476(US20230286978, Example 12)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618474(US20230286978, Example 10)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618469(US20230286978, Example 5)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618468(US20230286978, Example 4)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618465(US20230286978, Example 1)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616042(US20230271957, Example 19)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616040(US20230271957, Example 17)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616039(US20230271957, Example 16)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616038(US20230271957, Example 15)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616037(US20230271957, Example 14)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616036(US20230271957, Example 13)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616035(US20230271957, Example 12)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616034(US20230271957, Example 11)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616033(US20230271957, Example 10)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616032(US20230271957, Example 9)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616017(US20230271957, Example 7)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616002(US20230271957, Example 6)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM615974(US20230271957, Example 3)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651661(US20240051939, Compound I-1)
Affinity DataIC50:  300nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651662(US20240051939, Compound I-2)
Affinity DataIC50:  300nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616043(US20230271957, Example 20)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM615916(US20230271957, Example 1)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616041(US20230271957, Example 18)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618477(US20230286978, Example 13)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618475(US20230286978, Example 11)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618473(US20230286978, Example 9)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618470(US20230286978, Example 6)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618467(US20230286978, Example 3)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618466(US20230286978, Example 2)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM616031(US20230271957, Example 8)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50542876(CHEMBL4647174 | US20230414581, Compound 3)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | US20230414581, Co...)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM642519(US20230414581, Compound 2)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50384774(CHEMBL1917204 | US20230414581, Compound 6)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM642523(US20230414581, Compound 5)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM642521(US20230414581, Compound 4)
Affinity DataIC50: <1.00E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM618471(US20230286978, Example 7)
Affinity DataIC50:  3.00E+3nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco s PBS buffer in a final assay volume of 20 無. ARM-SAM-TIR lysate wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM615990(US20230271957, Example 5)
Affinity DataIC50:  3.00E+3nMAssay Description:The enzymatic assay was performed in a 384-well polypropylene plate in Dulbecco's PBS buffer in a final assay volume of 20 μL. ARM-SAM-TIR l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM47032(2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl...)
Affinity DataIC50:  3.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM47032(2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl...)
Affinity DataIC50:  3.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50365735(CHEMBL33859 | MKT-077 | US20230414581, Compound 39)
Affinity DataIC50:  5.50E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM642528(US20230414581, Compound 8)
Affinity DataIC50:  5.50E+3nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50:  7.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50:  8.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetNAD(+) hydrolase SARM1(Homo sapiens)
Disarm Therapeutics

US Patent
LigandPNGBDBM50439674(RICOLINOSTAT | US10858323, Compound 2 | US11207431...)
Affinity DataIC50: >1.00E+4nMAssay Description:First, 200 μM of the compound was added to a 50 mM Tris-HCl (pH 7.5) solution containing 0.05 μg/ml dN-SARM1. Then half of the mixture was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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